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Effects of bile acids in nutrition of sows and piglets

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掃一掃!Effects of bile acids in nutrition of sows and piglets掃一掃!
瀏覽:- 發布日期:2019-09-16 16:02:28【

Yang Xiaofei

Abstract: At present, bile acids plays an important role in animal husbandry, such as promoting the digestion and absorption of fat and fat-soluble substances, saving energy, promoting animal growth, improving carcass quality, preventing and treating liver and gallbladder diseases. The key to the profitability of pig farms lies in the level of sow and piglet management, and the value of sow is mainly reflected by piglets. Therefore, the industry puts forward the concept of "sow and piglet integration, SPI" nutrition from the perspective of systematic nutrition program. The application effect of bile acids in feed products sow and piglets was reviewed in this paper.

搜狗截圖19年09月16日1610_7

Key Words:bile acids, reproductive performance, growth performance, sow and piglets integration

子弹视频 Thecommon problems in the breeding process of sows and piglets

子弹视频 In the process of large-scale and intensive breeding, farmers will face the following problems of sows and piglets: sows' lacrimal blotches, old skin, rust lines, piglets' skin, piglets' messy and dull color, etc. Sow feed intake is low, constipation, mastitis, milk yield, low intake of piglets, diarrhea rate is high, low birth weight, weaned weight, growth retardation, higher feed conversion ratio and common reproductive performance, sows and piglets production performance problems, these problems are all over the world feed and breeding the common problems of the enterprise, the development of pig industry has certain constraints.

Causes analysis of common problems in sows and piglets

It was found that the common problems of sows and piglets were related to physiology, pathology, feed, environment, stress and autoimmunity.

子弹视频 Lacrimal blotches, rust-colored bleeding on the back, messy fur and other problems are common in lactating sows, which are often related to the accumulation of toxins in sows' bodies and the impaired ability of liver detoxification and detoxification. On the one hand, the accumulation of toxins in sows causes a large increase in bacterial endotoxin, intestinal microbial imbalance, and continuous constipation in sows. On the other hand, toxins accumulate in piglets through placenta and milk, further aggravating the liver damage of piglets. Liver damage leads to insufficient bile acid secretion, and piglets cannot digest the fat in milk and feed, leading to the occurrence of hepatogenic diarrhea.

Weaning piglets at 3 to 4 weeks or even before 3 weeks has been widely used in modern breeding. At this stage of the volume and weight of the piglets digestive tract and digestive gland has reached maturity level, weaning feed structure has changed dramatically, also can absorb by breast milk is about 22.18 MJ dropped to 13.8 to 14.5 MJ weaning diet (in terms of dry matter per kilogram), the diet for containing the antigens by extremely easy digestion and absorption of breast milk change, antinutritional factors more, extremely easy digestion and absorption of grain - type soybean meal diet types, starch, protein, fat in the diet is not easy to peptic with this stage piglets digestive enzymes in the body, the shortage of the secretion of bile acid stress, easy to cause severe weaning piglets Causes intestinal injury and inflammation in piglets, resulting in diarrhea, low feed intake, pale skin, messy coat color, and slow growth.

The Physiological function of bile acids

Bile acids, a feed additive, is a steroid-like substance found in bile and is the main organic component of bile. The current study found that bile acids promote the absorption of cholesterol, lipids and fat-soluble vitamins in the intestine. In addition, the bile acid is also an important signal regulating molecule, can activate specific nuclear receptors in liver and gastrointestinal cell method, ester X receptor (FXR Farnesoid X receptor), G protein coupled receptors and signaling pathways, which changes with the coding regulation of bile acid, glucose, fatty acids and lipoprotein synthesis, metabolism, transport and energy metabolism related enzyme (protein) gene expression. The main functions of bile acids in animals include: 1) participating in the digestion and absorption of fats and fat-soluble substances, emulsifying, activating lipase and transporting fatty acids in the process of fat digestion and absorption; 2) bile acids are mainly found in the enterohepatic circulation system and which promote the excretion of liver and intestinal toxins through recycling to protect the liver and intestinal function and health; 3) bile acids in the liver have the function of maintaining cholesterol balance; 4) bile acid in the intestinal has antibacterial and anti-inflammatory functions.

子弹视频 Theeffect of bile acids in feed ofsow and piglet

The use of bile acids in sow feed can improve the quality of sow colostrum (reducing cholesterol in colostrum, increasing the content of triglycerides and total protein in colostrum significantly), increasing the weaning weight of piglets significantly,affects the secretion of serum-related hormones in weaned piglets (cortisol levels in serum of weaned piglets are significantlydecreased (P < 0.05), and insulin, T3 and T4 levels are significantly increased).

子弹视频 • The effect of bile acids to lactating sow diet on biochemical indexes of colostrum

Table 1 shows that triglycerides in the colostrum of the 50 ppm, 100 ppm, 150 ppm, and 200 ppm groups were significantly increased compared with control group (P < 0.05). The total protein in the colostrum of the 100 ppm, 150 ppm, and the 200 ppm in the sow diet supplemented with bile acids was significantly increased compared with the control group(P < 0.05).

子弹视频 Table 1 Effect of bile acids addition on the biochemical parameters of colostrum in 

表格

• Effect of bile acids to lactating sow diet on weaning weight of piglets

子弹视频 Table 2 shows that compared with the control group, the weaning weight of the sow diet with bile acids 100ppm, 150ppm and 200ppm was significantly increased (P < 0.05), and the 50ppm group showed an increasing trend. The results showed that the addition of bile acids to the sow diet increased the weight of weaned piglets.

表格1

• Effect of bile acids on the intestinal digestibility of nutrients in weaned piglets

子弹视频 The application of bile acids in piglet feed can improve the growth performance, improve the intestinal digestive rate of nutrients in piglets, and affect the secretion of serum related hormones in piglets.

子弹视频 As shown in Table 3, the apparent digestibility of crude protein of weaned 

子弹视频 piglets in bile acids group was increased compared with the control group. The apparent digestibility and total energy digestibility of crude fat in the 80~100 mg/kg bile acids treatment group were significantly improved, and the apparent digestibility of dry matter was significantly improved.

表格3

Note: There is a significant difference between the different lowercase letters in the peer data (P < 0.05); the absence of a letter or the same letter indicates that the difference is not significant (P > 0.05).

Mechanism of bile acids improving sow reproductive performance and growth performance of piglets

The addition of bile acids to lactating sow diet increased the content of triglyceride and total protein in colostrum significantly, increased the apparent digestibility of crude protein, crude fat, dry matter and total energy in weaned piglets, and significantly increased the weaning weight of piglets. This is related to bile acids as an important signal-regulating molecule, regulating the physiological functions of synthesis, metabolism, transportation and energy metabolism of glucose, fatty acids and lipoproteins; bile acids involved in the whole process of emulsification, digestion and absorption of fat as a digestive juice ;

In addition, bile acids is also an excretory fluid, which is mainly found in the intestinal circulatory system and promotes the excretion of liver and intestinal toxins, antibacterial and anti-inflammatory effects through recycling, thereby achieving the function of protecting liver and intestinal function.

搜狗截圖19年09月16日1609_6

子弹视频 Conclusion

RUNEON, the main ingredient isbile acids,which is a patented functional feed additive of Shandong Longchang Animal Health Products Co., Ltd. Bile acids can make up for the lack of bile acids secretion of livestock and poultry, releasing the potential energy of feed. Bile acids also has the functions of promoting fat digestion and absorption, protecting liver and intestinal health, improving feed utilization, reducing feed cost, ensuring health and improving the reproduction and production performance of livestock and poultry, and will play an important role in the sow and piglet integration.

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